Stress is crucial to the survival of an organism, but excessive stress can lead to psychological disorders including depression, anxiety, substance abuse, and suicidality.The prevailing notion is that chronic stress promotes adverse outcomes on brain and body health, whereas acute stressors are generally benign.Notably, acute events such mass shoot
Partial C4 deficiency in two children with systemic lupus erythematosus
Systemic lupus erythematosus (SLE) is a rare disease in childhood.Here two cases with SLE are presented, both Sleeves with C4 null alleles yielding a functional C4 deficiency.The first case, a 14-year-old girl with a C4A null allele only, had a mild disease course, whereas the second child, a seven-year-old boy with both C4A0 Hair and scalp treatme
Anatomical notes and discussion of the first described aetosaur Stagonolepis robertsoni (Archosauria: Suchia) from the Upper Triassic of Europe, and the use of plesiomorphies in aetosaur biochronology
Stagonolepis robertsoni, from the Late Triassic of Scotland, was the first named aetosaurian.Known mostly from a series of natural molds from two localities, the osteology of this taxon STRONG HOLD AND HIGH SHEEN has been difficult to interpret.Detailed work on this material in the late 1950s resulted in a monograph that set the standard for the un
THE IMPACT OF FERTILIZATION AND FOLIAR STIMULATION PRODUCTS BOTH ON INCREASING THE RESISTANCE TO MAJOR PHYTOPATHOGENS ATTACKS, AND ON INCREASING THE QUANTITY AND QUALITY OF WINE GRAPES HARVEST
The paper aimed to demonstrate the impact of fertilization and foliar stimulation products both on increasing the resistance to major phytopathogens attacks, and on increasing the quantity and quality of wine grapes harvest.Applying the foliar fertilizer products Plonvit Kali (c1), Tytanit (c2) and Optysil (c3) to STRONG HOLD AND HIGH SHEEN vines,
MicroRNA-770-5p contributes to podocyte injury via targeting E2F3 in diabetic nephropathy
Diabetic nephropathy (DN) has been identified as the major cause of end-stage renal disease (ESRD) in most developed countries.MicroRNA-770-5p depletion could repress high glucose (HG)-triggered apoptosis in podocytes, and downregulation of E2F transcription factor 3 (E2F3) could facilitate podocyte injury.Nevertheless, whether E2F3 is involved in